What is a Sublingual or Oral medication? February 20, 2024 21:09 Updated This is medication that is delivered via your mouth. Specifically, sublingual medication is delivered underneath the tongue. Related articles Is Sublingual GLP-1 as effective as injectable GLP-1? What is compounded semaglutide, and how can it help with weight loss? Should my GLP-1 Sublingual / Oral medication be refrigerated? Can I get Ondansetron (Zofran) if I am nauseous? Why is my vial only half full?