Should my GLP-1 medication be refrigerated? February 20, 2024 21:09 Updated Yes. In order to keep the medication safe and effective, it needs to be refrigerated after it is delivered. Related articles Why is my syringe too small to deliver my dose in one injection? How does Henry Meds ensure the safe delivery of temperature-sensitive medications? What is compounded semaglutide, and how can it help with weight loss? Why is my vial only half full? Is Sublingual GLP-1 as effective as injectable GLP-1?